Senior Researcher, Department of Virology, Institute of Veterinary Research and Development of central Vietnam (IVRD), No. 227, 2/4 street, Vinh Hoa ward, Nha Trang City, Khanh Hoa, Vietnam
Email: dotan.vet@gmail.com
Orcid: https://orcid.org/0000-0003-4512-7622
About me
I am interested in isolation and genetic characterization of pathogens in animals, especially infectious viruses. Applying novel and advanced technologies in development of conventional and new-generation vaccines against infectious and emerging diseases is my passion.
Qualifications
2015 – 2020: PhD (Veterinary Medicine), Kangwon National University, South Korea
2005 – 2010: Doctor of Veterinary Medicine, Vietnam National University of Agriculture, Vietnam
Employment
2020 – now : Senior researcher, Department of Virology, IVRD
2013 – 2015: Researcher, Department of Virology, IVRD
2010 – 2012: Researcher, Department of Biotechnology, IVRD
Research expertise
Infectious and emerging diseases, Recombinant proteins, Immulogy and Vaccine development
Languages
- Vietnamese (native)
- English (fluent)
Projects
- ASEAN virus genome analysis, database construction, infection mechanism and diffusion model research for preemptive response too new and variant viruses of concern for domestic invasion. International project with South Korea. (Principal investigator, 2022-2023)
- Producing bivalent inactivated vaccine against Parvovirus and Erysipelothrix rhusiopathiae in swine, funded by Ministry of Agriculture and Rural Development. (Senior researcher, 2022-2025)
- Genetic and proteomic analysis of porcine epidemic diarrhea virus and its vaccine development. (PhD candidate, 2015-2020)
- Investigate the prevalence of porcine reproductive respiratory syndrome disease, determine the resistance ability against the disease in pigs vaccinated against swine cholera, pasteurellosis and typhoid fever and propose the prevention strategies for pigs bred in Khanh Hoa, funded by Science and Technology Khanh Hoa. (Researcher, 2014-2016)
- Research to develop a recombinant vaccine against Edema disease and Salmonellosis in pigs. Ministry of Agriculture and Rural Development. (Researcher, 2013-2014)
- Study on the prevalence of Duck Hepatitis Virus in some central provinces and assessment of efficacy of some egg yolk antibodies products on the market. Ministry of Agriculture and Rural Development. (Researcher, 2012-2013)
- Selection of highly pathogenic porcine reproductive and respiratory syndrome viruses for vaccine development. International project with MJ Biologics Inc., USA. (Main researcher, 2010-2013)
Publications
- Van Tan Do, Quang Lam Truong, Hoai Thu Dao, Thi Lan Nguyen, Jini Kim, Tae-Wook Hahn. Isolation, characterization and neutralizing activity of porcine epidemic viruses from Vietnam. Korean Journal of Veterinary Research; 2021; 61 (3):e23.https://doi.org/10.14405/kjvr.2021.61.e23
- Hoai Thu Dao, Woo-Sung Shin, Van Tan Do, Quang Lam Truong, Jong-Young Choi and Tae-Wook Hahn. A multivalent vaccine containing Actinobacillus pleuropneumoniae and Mycoplasma hyopneumoniae antigens elicits strong immune respomses and promising protection in pigs. Journal of Pure and Applied Microbiology; 2021; 15(1):164-174. https://doi.org/10.22207/JPAM.15.1.11
- Van Tan Do, Jisung Jang, Jeongho Park, Hoai Thu Dao, Kiju Kim, Tae-Wook Hahn. Recombinant adenovirus carying a core neutralizing epitope of porcine epidemic diarrhea virus and heat-labile enterotoxin B of Escheria coli as a mucosal vaccine. Archives of Virology; 2020; 165:609-618. doi: 1007/s00705-019-04492-7
- Van Tan Do, Hoai Thu Dao, Tae-Wook Hahn. Generation of a cold-adapted PRRSV with a nucleotide substitution in the ORF5 and numerous mutations in the hypervariable region of NSP2. Journal of Veterinary Science; 2020; 21(6):e85. doi: 4142/jvs.2020.21.e85
- Hoai Thu Dao, Quang Lam Truong, Van Tan Do, Tae-Wook Hahn. Construction and immunization with double mutant ΔapxIBD Δpnp forms of Actinobacillus pleuropneumoniae serotypes 1 and 5. Journal of Veterinary Science; 2020; 21(2):e20. doi: 4142/jvs.2020.21.e20
- Hoai Thu Dao, Van Tan Do, Quang Lam Truong, Tae-Wook Hahn. Enhancement of Apx toxin production in Actinobacillus pleuropneumoniae serotypes 1, 2, and 5 by optimizing culture conditions. Journal of Microbiology and Biotechnology; 2020; 30(7):1037-1043. doi: 4014/jmb.1912.12042
- Jong-Young Choi, Kwang-Soo Lyoo, Kiju Kim, Van Tan Do, Kyung-Won Lee, Tae-Wook Hahn. A pilot comparative study of Recombinant protein and whole-virus inactivated vaccines against porcine circovirus type 2 in conventionally reared pigs. Research in Veterinary Science; 2019; 123:192-194. doi: 1016/j.rvsc.2019.01.002
- Nguyen Duc Tan, Vu Khac Hung, Byoung Kwan Kim, Do Van Khien, Do Van Tan. Isolation and selection of some highly pathogenic porcine reproductive and respiratory syndrome viruses for vacciine produuction. Journal of Veterinary Sciences and Techniques; 2015; 2; 24-32. (in Vietnamese)
- Vu Khac Hung, Do Van Tan, Ho Van Hiep, Nguyen Thi Thu Hang. Evaluation of stability of some porcine reproductive and respiratory syndrome viruses in D1-China group. Journal of Veterinary Sciences and Techniques; 2015; 3; 15-19. (in Vietnamese)
- Pham Hung, Do Van Khien, Dang Thanh Hien, Pham Thi Bich Lien, Do Van Tan. Prevalence of Duck hepatitis virus in bred ducks in South Central. Journal of Veterinary Sciences and Techniques; 2014; 3; 5-10. (in Vietnamese)
- Vu Khac Hung, Dao Hoai Thu, Do Van Tan, Nguyen Thi Thu Thuy, Nguyen Xuan Truong, Hoang Huy Hoa, Nguyen Thi Kim Phung. Research on making attenuated Salmonella Choleraesuis strain carrying recombinant plasmid cloned two antigens of Escherichia coli. Journal of Veterinary Sciences and Techniques; 2013; 6. (in Vietnamese)
- Bui Thi Ba, Dao Hoai Thu, Vo Thanh Thin, Dang Van Tuan, Do Van Tan, Vu Khac Hung. Genetic analysis of antimicrobial resistance in Escherichia coli O157:H7 isolated from healthy cattle and buffaloes in Central Vietnam. Journal of Veterinary Sciences and Techniques; 2012; 6; 50-62. (in Vietnamese)
- Bui Thi Ba, Dao Hoai Thu, Do Van Tan, Hoang Huy Hoa, Vu Khac Hung. Analysis on genetic variation of Shiga toxin gene in Echerichia coli O157:H7 strain isolated from healthy cattle and buffaloes in some provinces in central Vietnam. Journal of Veterinary Sciences and Techniques, 2012; 3; 29-34. (in Vietnamese)
- Nguyen Thi Thinh, Lam Thi Hue, Dao Hoai Thu, Hoang Huy Hoa, Do Van Tan, Nguyen Xuan Truong, Ho Van Hiep, Vu Khac Hung. Construction and characterization of a salmonella choleraesuis Smith Δcrp deletion mutant. Vietnam Journal of Agriculture & Rural Development; 2012; 8.
- Nguyen Trong Hai, Dao Hoai Thu, Phan Thi Hang, Ho Van Hiep, Nguyen Thi Kim Phung, Do Van Tan, Le Dinh Hai, Vu Khac Hung. The prevalence and antibiotic resistance of E. coli O157:H7 strains isolated from healthy cattle and buffaloes in some provinces of Central Vietnam. Journal of Veterinary Sciences and Techniques; 2011; 3; 31-37. (in Vietnamese)
- Nguyen Trong Hai, Dao Hoai Thu, Phan Thi Hang, Ho Van Hiep, Nguyen Thi Kim Phung, Do Van Tan, Le Dinh Hai, Vu Khac Hung. Determination of coli infection prevalence in apparently healthy cattle in the Center of Vietnam and of antibiotic resistance of this bacterium. Vietnam Journal of Agriculture & Rural Development; 2011; 173; 63-67. (in Vietnamese)
Conferences
- Phylogenetic analysis of emerging infectious viruses in pigs and cattle during 2019-2022 in Vietnam (2022, ISIFS 2022, South Korea)
- Isolation, characterization and neutralizing activity of porcine epidemic viruses from Vietnam (2019, APVS 2019, South Korea)
- Deletion of gshB virulence factor attenuates Brucella canis and confers protection against the challenge with virulent B.canis (2016, 2016 Zoonotic Diseases, South Korea)
Teaching
- Tutor and trainer for Animal Infectious Viruses for undergraduate students at Kangwon National University, South Korea (2018-2020)
Supervision
- Co-supervised two undergraduate students
Awards and Grants
- Outstanding Academic Award of Kangwon National University, South Korea (2020)